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Symbol
Name
ID

Foxf1
forkhead box F1
MGI:1347470

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes

Single umbilical artery

Atrial septal defect

Patent foramen ovale

Ventricular septal defect

Atrioventricular canal defect

Right ventricular hypertrophy

Tetralogy of Fallot

Bicuspid aortic valve

Parachute mitral valve

Dysplastic tricuspid valve

Pulmonary valve atresia

Hypoplastic left heart

Hypoplastic aortic arch

Interrupted aortic arch

Coarctation of aorta

Pulmonary artery dilatation

Pulmonary artery stenosis

Partial anomalous pulmonary venous return

Misalignment of the pulmonary veins

Persistent left superior vena cava

Patent ductus arteriosus

Pulmonary lymphangiectasia

Pulmonary insufficiency

Pulmonary arterial hypertension

Right-to-left shunt

Asplenia

Disease(s) Associated with FOXF1

persistent fetal circulation syndrome

Mouse Phenotypes		abnormal pulmonary artery morphology	decreased vascular endothelial cell number	abnormal lung vasculature morphology	abnormal vascular branching morphogenesis	decreased angiogenesis	absent vitelline blood vessels	abnormal pulmonary vein morphology	lung hemorrhage
Availability	Mouse Genotype	abnormal pulmonary artery morphology	decreased vascular endothelial cell number	abnormal lung vasculature morphology	abnormal vascular branching morphogenesis	decreased angiogenesis	absent vitelline blood vessels	abnormal pulmonary vein morphology	lung hemorrhage
	Foxf1^tm1Pca/Foxf1^tm1Pca
	Foxf1^em1Vvk/Foxf1⁺
	Foxf1^tm1Rhc/Foxf1⁺
	Foxf1^tm1.1Vvk/Foxf1^tm1.1Vvk Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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